Advancing the Science
of Nerve Repair, Naturally
KLISBio® is advancing peripheral nerve repair, naturally, with SILKBridge®, the first-of-its-kind Biointegrative Nerve Guide bioengineered from silk fibroin. Designed to guide and structurally support axonal growth across a nerve gap, SILKBridge features a proprietary Tri-Layer™ architecture with a semipermeable wall that enables cellular infiltration and remodeling, resists compression, and integrates with native nerve tissue. Soft, flexible, and ready off the shelf, SILKBridge offers surgeons a biointegrative approach to nerve repair.
WHY SILK?
Silk fibroin is a uniquely versatile biomaterial with a long history in medicine. Its biocompatibility, paired with a rare balance of biological and mechanical performance, makes it well suited for applications that require both structural support and integration with native tissue
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Outstanding mechanical and biological properties
Versatile processing and design flexibility
Tailored degradation profiles
Acellular by design, with no residuals
Bioengineered for cellular attachment and growth
Supports a regenerative environment that promotes neovascularization
SILKBridge® is a biointegrative nerve guide designed for the surgical repair of peripheral nerve discontinuities. Bioengineered from silk fibroin, it features a proprietary Tri-Layer™ architecture with a semipermeable, micro/macro-porous wall designed to guide and structurally support axonal growth across a nerve gap while enabling cellular infiltration, remodeling, and integration with native nerve tissue. Soft, flexible, and biomechanically aligned with the handling needs of nerve repair, SILKBridge also offers the practical simplicity of a sterile, single-use, off-the-shelf implant.
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ABOUT US
KLISBio is a medtech company developing implantable regenerative solutions powered by silk fibroin. By combining material science, bioengineering, and deep surgical focus, KLISBio is advancing a new approach to soft tissue repair designed to work in harmony with the body’s own healing processes.
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